HOUSE.
The characters are all slightly annoying, and the show is so unbelievable, but for some reason I'm so totally hooked on it. I'm not even a doctor / med student and I know that some of the medicinial talk is ridiculous.
Last night I started on Season 2 - I finished season 1 in about a week.
I think it must have something to do with how delightfully cynical House's character is.